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Saudi Journal of Kidney Diseases and Transplantation
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Year : 2015  |  Volume : 26  |  Issue : 3  |  Page : 437-442
Light chain nephropathy


1 Foetopathology Unit, Habib Bougatfa Hospital, Bizerte, Tunisia
2 Department of Immunohistocytology, Salah Azaiez Institute, Tunis, Tunisia
3 Department of Nephrology and Internal Medicine, Charles Nicolle Hospital, Tunis, Tunisia

Correspondence Address:
Dr. Sihem Darouich
Foetopathology Unit, Habib Bougatfa Hospital, Bizerte
Tunisia
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DOI: 10.4103/1319-2442.157296

PMID: 26022011

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Light chain deposition disease (LCDD) is characterized by the tissue deposition of monotypic immunoglobulin light chains of either kappa or lambda isotype. It is the archetypal systemic disease that is most frequently diagnosed on a kidney biopsy, although the deposits may involve several other organs. This brief review focuses on the clinicopathological features of LCDD-associated nephropathy with an emphasis on the diagnostic and therapeutic difficulties related to this elusive condition.


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