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Saudi Journal of Kidney Diseases and Transplantation
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RENAL DATA FROM ASIA - AFRICA Table of Contents   
Year : 2015  |  Volume : 26  |  Issue : 6  |  Page : 1241-1245
Urinary screening for asymptomatic renal disorders in pre-school children in Enugu metropolis, South-east Nigeria: Useful or useless


1 Pediatric Nephrology Unit, Department of Pediatrics, University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu, Nigeria
2 Pediatric Surgery Unit, Department of Surgery, Enugu State University Teaching Hospital, Enugu, Nigeria
3 Department of Medical Biochemistry, College of Medicine, Enugu State University of Science and Technology, Enugu, Nigeria
4 Department of Radiation Medicine, University of Nigeria Teaching Hospital, Enugu, Nigeria
5 Department of Pediatrics, Enugu State University Teaching Hospital, Enugu, Nigeria

Correspondence Address:
Odutola Israel Odetunde
Pediatric Nephrology Unit, Department of Pediatrics, University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu, Enugu State
Nigeria
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DOI: 10.4103/1319-2442.168656

PMID: 26586065

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To evaluate the usefulness of simple screening tests such as urinalysis and blood pressure measurement in the early detection of renal disorders in pre-School children, we used a multi-staged random sampling method to select subjects from registered nursery schools within Enugu metropolis in south-east Nigeria. We selected 630 children for this cohort study. There was a prevalence of 2.7%, 0% and 1.9% for asymptomatic proteinuria, hematuria and hypertension, respectively. There was no age, gender or social class preponderance (P = 0.44). Hypertension seemed to be limited to children close to the age group of five years (P <0.001). No correlations could be documented between asymptomatic proteinuria, hematuria or hypertension. The prevalence of persistent proteinuria was found to be 1.6% and the mean urinary protein excretion estimation (spot urine protein/creatinine) was 1.88 g/mg ± 0.53, with a mean glomerular filtration rate of 78.7 ± 12.6 mL/min/1.73 m 3 . Renal ultrasonography revealed abnormal findings in 30% of the children with persistent proteinuria. Asymptomatic persistent proteinuria with or without hematuria and hypertension could be a presumptive evidence of an underlying renal parenchymal disease and should be properly investigated and followed-up.


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