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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2015  |  Volume : 26  |  Issue : 6  |  Page : 1262-1265
Wegner's granulomatosis developing for the first time in a patient eight years after starting maintenance hemodialysis


1 Department of Medicine, Al-Amiri Hospital, Kuwait University, Safat, Kuwait, Kuwait
2 Department of Medicine, Faculty of Medicine, Kuwait University, Safat, Kuwait

Correspondence Address:
Kamel El-Reshaid
Department of Medicine, Faculty of Medicine, Kuwait University, P O Box 24923, 13110 Safat
Kuwait
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DOI: 10.4103/1319-2442.168666

PMID: 26586069

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Wegener's granulomatosis is a serious autoimmune disorder characterized by necrotizing small-vessel vasculitis. It is a multisystem disease that primarily affects the lung and kidneys. Previous studies indicated few relapses of vasculitis after hemodialysis due to uremic immunosuppression. Our case report describes an end-stage renal failure patient who had developed non-caseating lung granulomata with giant cell formation and fibrinoid necrosis of arterial media that is consistent with Wegner's granulomatosis for the first time and eight years after initiation of maintenance hemodialysis. We believe that such a phenomenon has rarely been reported.


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