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| ORIGINAL ARTICLE |
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| Year : 2017 |
Volume
: 28 | Issue : 3 | Page
: 477-482 |
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Carnitine reduced erythropoietin dose required and improved cardiac function of patients on maintenance hemodialysis
Yosuke Aoki1, Takako Yamamoto2
1 Department of Biochemistry, Institute of Medullasin, Kamakura; Fureai Clinic Izumi, Yokahama, Kanagawa, Japan
2 Department of Biochemistry, Institute of Medullasin, Kamakura, Japan
Correspondence Address:
Yosuke Aoki
Department of Biochemistry, Institute of Medullasin, Kamakura, Kanagawa
Japan
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DOI: 10.4103/1319-2442.206445 PMID: 28540882 
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Intravenous administration of 2 g carnitine in every hemodialysis (3 times/week), for 8–10 months, reduced doses of darbepoetin alfa required to maintain adequate hemoglobin levels (10–11 g/dL) into 10% of the initial doses. There was also a significant increase in plasma transferrin saturation, increase in left ventricular ejection fraction, and decrease in plasma brain natriuretic peptides. |
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