Home About us Current issue Ahead of Print Back issues Submission Instructions Advertise Contact Login   

Search Article 
Advanced search 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 802 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 

Year : 2019  |  Volume : 30  |  Issue : 1  |  Page : 194-201
Frequency of pregnancy-related complications causing acute kidney injury in pregnant patients at a tertiary care hospital

1 Department of Nephrology, Jinnah Postgraduate Medical Center, Karachi, Pakistan
2 Department of Nephrology, The Kidney Centre Postgraduate Training Institute, Karachi, Pakistan

Correspondence Address:
Murtaza F Dhrolia
Department of Nephrology, The Kidney Centre Postgraduate Training Institute, Karachi 75530
Login to access the Email id

DOI: 10.4103/1319-2442.252910

PMID: 30804281

Rights and Permissions

Acute kidney injury (AKI) in pregnancy is associated with significant maternal morbidity and mortality. Several studies from worldwide have shown different frequencies of the causes of pregnancy-related AKI (PRAKI). The present study aimed to provide local data on frequency of causes of PRAKI. A total of 111 pregnant women using nonprobability consecutive sampling technique, with the age group of 18–45 years, admitted with the diagnosis of PRAKI were included in the study. The information regarding age, duration of pregnancies, serum creatinine levels, and outcome variables (complications) were collected from each patient. Effect modifiers were controlled by stratification. The mean age was 29.90 ± 5.40 years. Out of 111 cases, 10 (9%) developed AKI in the 1st trimester, 12 (10.8%) in the 2nd trimester, 13 (11.7%) cases in the 3rd trimester, and rest of the 76 (68.4%) cases were of the postpartum period. The etiology of PRAKI was multifactorial in several patients. The frequencies of complication leading to AKI were observed individually. The results showed that 21 (18.9%) had antepartum hemorrhage, 41 (36.9%) postpartum hemorrhage, 33 (29.7%) puerperal sepsis, 11 (9.9%) preeclampsia, 13 (11.7%) eclampsia, 11 (9.9%) hemolysis, elevated liver enzymes, and low-platelet count syndrome, 7 (6.3%) hemolytic uremic syndrome, and 5 (4.5%) had hyperemesis gravidarum. The results of the present study showed no statistically significant association of age with the individual complications with P >0.05. AKI during pregnancy was mostly due to prerenal causes. The most common cause was postpartum hemorrhage followed by puerperal sepsis and antepartum hemorrhage.

Print this article  Email this article

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded298    
    Comments [Add]    

Recommend this journal