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Saudi Journal of Kidney Diseases and Transplantation
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Year : 2019  |  Volume : 30  |  Issue : 1  |  Page : 273
Human parechovirus infection related renal failure: A new emerging problem

1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Dr. DY Patil University, Pune, Maharashtra, India

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Date of Submission11-Jul-2018
Date of Acceptance14-Jul-2018
Date of Web Publication26-Feb-2019

How to cite this article:
Joob B, Wiwanitkit V. Human parechovirus infection related renal failure: A new emerging problem. Saudi J Kidney Dis Transpl 2019;30:273

How to cite this URL:
Joob B, Wiwanitkit V. Human parechovirus infection related renal failure: A new emerging problem. Saudi J Kidney Dis Transpl [serial online] 2019 [cited 2021 Oct 26];30:273. Available from: https://www.sjkdt.org/text.asp?2019/30/1/273/252928

To the Editor,

The virus infection-related renal failure is an important condition in clinical nephrology. Many viruses, especially for the arboviruses, are mentioned for the possibility in the induction of renal failure.[1] Human parechovirus infection is a new emerging virus infection. The human parechovirus is usually reported in the infant and children with the febrile illness. The infection is usually mild, but the severe infection might be observed in some cases. In adult case, it might also induce diarrhea.[2] A recent study from Thailand showed that 0.3% of adult diarrhea was related to human parechovirus.[3] The sepsis-like condition is the main clinical problem in severe human parechovirus infection[3], and there is also other possible uncommon clinical manifestation including to renal failure.[4] The exact incidence of human parechovirus infection related renal failure is not well studied. According to a recent report from the UK, 3% of 104 hospitalized children with human parechovirus infections have a renal problem and requires dialysis treatment.[5] The exact pathomechanism of human parechovirus infection related to acute renal failure is unknown. However, the renal problem is usually observed as a complication of the septic episode in the affected patients. As a new emerging infection, the practitioner has to include the human parechovirus infection in any patients with sepsis-like problem and the good monitoring on renal function and fluid therapy is required for any diagnosed case for preventing unwanted renal complication.

Conflict of interest:

None declared.

   References Top

Wiwanitkit S, Wiwanitkit V. Renal failure due to important arbovirus infection: A short summary. Saudi J Kidney Dis Transpl 2017;28:1206-8.  Back to cited text no. 1
[PUBMED]  [Full text]  
Wiwanitkit V. Human parechovirus infection in the neonate and neurological disorder: A new disease. J Neuroinfect Dis 2015;6:e105.  Back to cited text no. 2
Saikruang W, Khamrin P, Suantai B, et al. Detection of diarrheal viruses circulating in adult patients in Thailand. Arch Virol 2014;159:3371- 5.  Back to cited text no. 3
Ollier V, Farfour E, Charara O, et al. Severe human parechovirus-3 sepsis in a 6-week-old infant. Arch Pediatr 2014;21:399-401.  Back to cited text no. 4
Braccio S, Kapetanstrataki M, Sharland M, Ladhani SN. Intensive care admissions for children with enterovirus and human parechovirus infections in the United Kingdom and the republic of Ireland, 2010-2014. Pediatr Infect Dis J 2017;36:339-42.  Back to cited text no. 5

Correspondence Address:
Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
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DOI: 10.4103/1319-2442.252928

PMID: 30804298

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