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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2020  |  Volume : 31  |  Issue : 2  |  Page : 528-532
Mesalazine induced focal segmental glomerulosclerosis in a patient with ulcerative colitis

1 Department of Nephrology, Antalya Atatürk State Hospital, Antalya, Turkey
2 Department of Nephrology, Liv Hospital, University of Istinye, Istanbul, Turkey
3 Department of Pathology, Akdeniz University, Faculty of Medicine, Antalya, Turkey
4 Department of Nephrology, Akdeniz University, Faculty of Medicine, Antalya, Turkey

Correspondence Address:
Fatih Yilmaz
Department of Nephrology, Antalya Atatürk State Hospital, Antalya
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DOI: 10.4103/1319-2442.284031

PMID: 32394929

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Focal segmental glomerulosclerosis (FSGS) and other glomerulonephritis due to the use of 5-aminosalicylic acid derivatives have been reported in the literature. A 38-year-old male who had been using mesalazine for four years because of ulcerative colitis applied to doctor due to swelling in the lower extremities. The patient was diagnosed with nephrotic syndrome (NS). Renal biopsy was performed, and FSGS was diagnosed. Antiproteinuric treatments were initiated with steroid therapy. The patient has been followed with the normal renal function of the after treatment. 5-aminosalicylic acid derivatives affect renal functions at different levels and caused in NS.

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