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Saudi Journal of Kidney Diseases and Transplantation
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Table of Contents   
LETTER TO THE EDITOR  
Year : 2021  |  Volume : 32  |  Issue : 5  |  Page : 1499-1500
The relationship of immunosuppressive adherence and disability levels among renal transplantation patients


1 Department of Psychology, Faculty of Social Sciences, Khenchela University, Khenchela, Algeria
2 Department of Psychology, Faculty of Human and Social Science, University of Batna 1, Batna, Algeria
3 Department of Health and Safety, University of Constantine 3, Constantine, Algeria

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Date of Web Publication4-May-2022
 

How to cite this article:
Aberkane S, Hamidani M, Baziz A. The relationship of immunosuppressive adherence and disability levels among renal transplantation patients. Saudi J Kidney Dis Transpl 2021;32:1499-500

How to cite this URL:
Aberkane S, Hamidani M, Baziz A. The relationship of immunosuppressive adherence and disability levels among renal transplantation patients. Saudi J Kidney Dis Transpl [serial online] 2021 [cited 2022 May 25];32:1499-500. Available from: https://www.sjkdt.org/text.asp?2021/32/5/1499/344778


To the Editor,

Algeria is the only country where all transplant recipients had free access to immunosuppressive agents and the only country where these drugs were available.[1] The World Health Organization describes several important factors in predicting adherence to long-term therapy with chronic illness patients, namely sociodemographic, clinical factors related to illness and treatment, psychosocial factors linked to the patient, and the health-care system levels related to factors.[2] Among these diseases, end-stage renal disease, which is one of the most widespread and complicated due to the health and psychological burdens, poses to patients as a result of dialysis therapy. Despite its proven effectiveness in improving the health condition of patients in general, it has many health risks. It is for that renal transplantation improves considerably the patient’s quality of life, with a dependence linked machine, and reduces morbidity-mortality versus those who remain on dialysis.[3] For example, Esposito et al’s study showed a direct relationship between kidney function during the 1st month after the transplant restrictions and physical, social, and emotional activities.[4] It was similar to Lorenz et al’s study.[5] That is why this study came to shed light on the relationship between therapeutic adherence and health-related quality of life with kidney transplantation patients, especially with the absence of Arab researches in this field. The main aim of this study is to assess the influence of therapeutic adherence on health-related quality of life among renal transplantation patients.

A cross-sectional design was adopted for this study among a sample of 60 individuals having renal transplantation, aged between 20 and 58 (mean age, 33.75 ± 8.49 years), and living in the region of Kais and Batna (Algeria); the data collection was between September 2018 and September 2019.

The study was approved by the Ethics Committee of the university, and informed consent was taken from all subjects before the study. Two scales are used: the Treatment Satisfaction with Medicines Questionnaire (SATMED-Q) divided into six subscales–CU, convenience of use; GS, global satisfaction; ID, impact on daily living/activities; MC, medical care; TE, treatment effectiveness; and UE, undesirable side effects– and the Short Form 36 version 2 scale divided into two subscales (mental component score and physical component score). The statistical correlation analysis is used to determine the relationship between therapeutic adherence and health-related quality of life. Multiple regression analysis is also used to assess the predictive ability of the therapeutic adherence dimensions on the health-related quality of life components.

This study has proved that there is an effect of the convenience of use (immunosuppressive), treatment effectiveness, and undesirable side effects on physical component score (R2 = 0.43, 0.63, and 0.68 respectively). There is an effect of high blood pressure, treatment effectiveness, and undesirable side effects on mental component score (R2 = 0.53, 0.38, and 0.61, respectively) [Table 1]. In conclusion, attention should be paid to these patients’ kind through trying to prepare therapy programs aimed to raise the patients’ health awareness, especially with the increasing prevalence of these surgical interventions currently in Algeria.
Table 1: Impact of immunosuppressive adherence on disability levels among sample patients.

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Conflict of interest: None declared.



 
   References Top

1.
WHO. African Health Report. Situation of Donation and Transplantation of Human Organs and Tissues in the WHO African Region. Geneva: WHO; 2020.  Back to cited text no. 1
    
2.
Kisa A, Sabaté E, Nuño-Solinís R. Adherence to Long-Term Therapies: Evidence for Action. Geneva, Switzerland: World Health Organization; 2003. Available from: https://www.researchgate. net/publication/318679616_ADHERENCE_T O_LONG-TERM_THERAPIES_Evidence_ for_action. [Last retrieved on 2020 Aug 09].  Back to cited text no. 2
    
3.
Kochar GS, Langone AJ. How should we manage renal transplant patients with failed allografts who return to dialysis? Blood Purif 2020; 49:228-31.  Back to cited text no. 3
    
4.
Esposito P, Furini F, Rampino T, et al. Assessment of physical performance and quality of life in kidney-transplanted patients: A cross-sectional study. Clin Kidney J 2017; 10:124-30.  Back to cited text no. 4
    
5.
Lorenz EC, Egginton JS, Stegall MD, et al. Patient experience after kidney transplant: A conceptual framework of treatment burden. J Patient Rep Outcomes 2019;3:8.  Back to cited text no. 5
    

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Correspondence Address:
Salah Aberkane
Department of Psychology, Faculty of Social Sciences, Khenchela University, Khenchela
Algeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1319-2442.344778

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