Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2004  |  Volume : 15  |  Issue : 4  |  Page : 489--493

Successful Bone Marrow Transplantation in a Child with X-Linked Hyper-IgM Syndrome


Haddadin Isam, A Al-Wahadneh 
 Department of Pediatrics, King Hussein medical Center, Amman, Jordan

Correspondence Address:
Haddadin Isam
Consultant Pediatric Oncologist, P.O.Box 926119, Amman 11190
Jordan

A 13-year-old boy was diagnosed at the age of three years as having hyper IgM Immunodeficiency syndrome (HIgM). It is a rare congenital disease characterized by recurrent infections and very low level of serum immunoglobulin (IgG, IgA) and elevated IgM. Conservative treatment with antibiotics and regular intravenous immunoglobulin (IVIG) was not satisfactory. At the age of five, the patient developed Hodgkin«SQ»s lymphoma, which was treated successfully with chemotherapy. Experience with Bone Marrow Transplantation (BMT) in such cases is limited as a definitive treatment for this kind of syndromes. He was transplanted from his HLA-matched sister, and three years post BMT follow-up he showed good clinical recovery and immunoreconstitution.


How to cite this article:
Isam H, Al-Wahadneh A. Successful Bone Marrow Transplantation in a Child with X-Linked Hyper-IgM Syndrome.Saudi J Kidney Dis Transpl 2004;15:489-493


How to cite this URL:
Isam H, Al-Wahadneh A. Successful Bone Marrow Transplantation in a Child with X-Linked Hyper-IgM Syndrome. Saudi J Kidney Dis Transpl [serial online] 2004 [cited 2021 Jan 22 ];15:489-493
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2004;volume=15;issue=4;spage=489;epage=493;aulast=Isam;type=0