Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2012  |  Volume : 23  |  Issue : 5  |  Page : 1024--1027

Severe pneumococcal hemolytic uremic syndrome in an 8-month-old girl


Tahar Gargah1, Majda Cherif2, Rim Goucha-Louzir2, Mohamed Rachid Lakhoua1 
1 Department of Pediatric Nephrology, Charles Nicolle Hospital, Tunis, Tunisia
2 Department of Nephrology, Charles Nicolle Hospital, Tunis, Tunisia

Correspondence Address:
Tahar Gargah
Department of Pediatric Nephrology, Boulevard 9 Avril, Charles Nicolle Hospital, Tunis, 1009
Tunisia

The hemolytic uremic syndrome (HUS), characterized by microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure, represents one of the major causes of acute renal failure in infancy and childhood. The typical form occurring after an episode of diarrhea caused by Escherichia coli is the most frequent in children. Other microorganisms also may be responsible for HUS, such as Streptococcus pneumoniae, which causes more severe forms of the disease. We report an 8-month-old girl who presented with pneumonia and subsequently developed HUS. Renal biopsy showed characteristic lesion of thrombotic microangiopathy and extensive cortical necrosis. She was managed with peritoneal dialysis but did not improve and developed severe sepsis due to staphylococcal peritonitis, resulting in the death of the patient. Streptococcus pneumoniae-induced HUS is uncommon, but results in severe disease in the young. There is a high risk of these patients developing end-stage kidney disease in the long term.


How to cite this article:
Gargah T, Cherif M, Goucha-Louzir R, Lakhoua MR. Severe pneumococcal hemolytic uremic syndrome in an 8-month-old girl.Saudi J Kidney Dis Transpl 2012;23:1024-1027


How to cite this URL:
Gargah T, Cherif M, Goucha-Louzir R, Lakhoua MR. Severe pneumococcal hemolytic uremic syndrome in an 8-month-old girl. Saudi J Kidney Dis Transpl [serial online] 2012 [cited 2022 Dec 9 ];23:1024-1027
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2012;volume=23;issue=5;spage=1024;epage=1027;aulast=Gargah;type=0