Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2014  |  Volume : 25  |  Issue : 3  |  Page : 634--637

ANCA-mediated crescentic glomerulonephritis with linear deposition of IgG along the glomerular basement membrane


Wiroon Sangsiraprapha1, Luan Truong2, Sreedhar Mandayam1 
1 Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
2 Department of Pathology, The Methodist Hospital, Houston, Texas, USA

Correspondence Address:
Dr. Sreedhar Mandayam
Department of Medicine, Baylor College of Medicine, Houston, TX 77030
USA

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides is an important cause of rapidly progressive glomerulonephritides (RPGN), and they are classically described as pauci-immune diseases as evidenced by the absence of immune deposits on immunofluoresence microscopy of the kidney biopsy. We report two patients with RPGN, pulmonary-renal syndrome, positive ANCA serology and linear Immunoglobulin G (IgG) staining on glomerular basement membrane in the absence of detectable anti-glomerular basement membrane (anti-GBM) antibodies in the serum.


How to cite this article:
Sangsiraprapha W, Truong L, Mandayam S. ANCA-mediated crescentic glomerulonephritis with linear deposition of IgG along the glomerular basement membrane.Saudi J Kidney Dis Transpl 2014;25:634-637


How to cite this URL:
Sangsiraprapha W, Truong L, Mandayam S. ANCA-mediated crescentic glomerulonephritis with linear deposition of IgG along the glomerular basement membrane. Saudi J Kidney Dis Transpl [serial online] 2014 [cited 2021 Apr 16 ];25:634-637
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2014;volume=25;issue=3;spage=634;epage=637;aulast=Sangsiraprapha;type=0