Saudi Journal of Kidney Diseases and Transplantation

LETTER TO THE EDITOR
Year
: 2014  |  Volume : 25  |  Issue : 3  |  Page : 655--656

Favorable survival rate after kidney transplantation in diabetic patients


Behzad Einollahi, Zohreh Rostami 
 Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, I.R. Iran

Correspondence Address:
Dr. Behzad Einollahi
Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran
I.R. Iran




How to cite this article:
Einollahi B, Rostami Z. Favorable survival rate after kidney transplantation in diabetic patients.Saudi J Kidney Dis Transpl 2014;25:655-656


How to cite this URL:
Einollahi B, Rostami Z. Favorable survival rate after kidney transplantation in diabetic patients. Saudi J Kidney Dis Transpl [serial online] 2014 [cited 2021 Dec 5 ];25:655-656
Available from: https://www.sjkdt.org/text.asp?2014/25/3/655/132227


Full Text

To the Editor,

We read with great interest the article by Rajaeefard et al [1] published in your esteemed journal entitled "Graft survival rate following renal transplantation in diabetic patients." This retrospective study focused its message on drawing the attention of nephrologists to whether diabetes mellitus (DM) has an adverse affect on renal allograft survival among kidney transplant patients.

Although Iran has the largest reported experience of kidney transplantation among the Middle East countries, [2] there are limited data available on DM in Iranian kidney recipients. It is of interest that the estimated 9-year graft survival rate in 103 diabetic kidney transplant patients was favorable (84.2%). We also reported the 5-year outcome of kidney transplantation in 117 patients with DM and 135 patients without DM. [3] There was no significant difference in graft survival between the two groups of recipients (log-rank, P = 0.9). We concluded that diabetic and non-diabetic kidney transplant recipients had similar short- and mid-term graft and patient survival rates. Multivariate analysis by Cox regression showed that age and gender of the recipient, donor source and DM had no adverse effect on mid-term outcome among our patients. Boucek et al reported a similar outcome in terms of 5-year patient and graft survival in diabetic and non-diabetic recipients. [4] Similar to previous reports, Rajaeefard et al [1] did not find a significant poorer patient survival in diabetic patients when compared with non-diabetic individuals. [5],[6],[7],[8]

In the past, clinicians tended to exclude diabetic patients from kidney transplantation due to the adverse effects of immunosuppressive drugs and high morbidity and mortality after surgery. Although the reported outcome of kidney transplantation is inferior for diabetic than for non-diabetic patients, [9] the survival of uremic diabetic patients who remained on chronic hemodialysis is significantly lower than diabetic transplant recipients. [10],[11] Nowadays, the number of diabetic patients is growing rapidly worldwide and kidney transplantation is generally accepted as a treatment of choice in these patients with end-stage renal disease (ESRD). In addition, it was demonstrated that the 1-year patient survival rate was similar in diabetic and non-diabetic transplant recipients, [6],[12] while others have shown that the 5-year patient survival rate was worse in diabetics compared with non-diabetic recipients. [13],[14],[15]

In summary, the study of Rajaeefard et al [1] and our study showed that diabetic patients with ESRD are not contraindicated for kidney transplantation and they carry a favorable and promising graft survival.

References

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