Saudi Journal of Kidney Diseases and Transplantation

: 2014  |  Volume : 25  |  Issue : 3  |  Page : 657--658

Authors reply

Manisha Sahay1, Rakesh Kumar Sahay2,  
1 Department of Nephrology, Osmania Medical College, Hyderabad, India
2 Department of Endocrinology, Osmania Medical College, Hyderabad, India

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How to cite this article:
Sahay M, Sahay RK. Authors reply.Saudi J Kidney Dis Transpl 2014;25:657-658

How to cite this URL:
Sahay M, Sahay RK. Authors reply. Saudi J Kidney Dis Transpl [serial online] 2014 [cited 2021 Dec 8 ];25:657-658
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To the Editor,

The letter from Wiwanitkit et al has highlighted the problems that can be encountered in conducting an oral glucose tolerance test (OGTT). However, our article and that of Sharif et al have shown that when only the fasting blood glucose is used, several patients with impaired glucose tolerance (IGT) and new onset diabetes after transplantation (NODAT) are missed. Hence, fasting glucose underestimates the prevalence of NODAT and ignores the prevalence of IGT. These findings suggest that the routine use of an OGTT in renal transplant recipients is a valuable clinical tool to risk- stratify each patient for the development of NODAT and cardiovascular disease.

The problems highlighted by Wiwanitkit et al have to be understood, and they should be over-come while performing the OGTT and during the interpretation of the results of the test.[5]


1Sahay M, Sahay RK, Narayan G; Anuradha. New-onset diabetes after transplantation - Role of oral glucose tolerance test for diagnosis and study of risk factors. Saudi J Kidney Dis Transpl 2013;24:897-902.
2Sharif A, Moore RH, Baboolal K. The use of oral glucose tolerance tests to risk stratify for new-onset diabetes after transplantation: An underdiagnosed phenomenon. Transplantation 2006;82:1667-72.
3Wiwanitkit V. Glucose tolerance test: A brief summary of basic principles and important considerations. Chula Med J 2006;50:825-30.
4Wiwanitkit V, Lekngarm P. Requisition errors for blood glucose tests: A hospital-based study. Lab Med 2007;38:559-60.
5Diagnostic pitfall. Fasting blood glucose in the normal range-but still diabetic. MMW Fortschr Med. 2002 Sep 5;144(35-36):56.