Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2014  |  Volume : 25  |  Issue : 4  |  Page : 864--868

Low-dose corticosteroid and gallium-67 scintigraphy and acute interstitial nephritis


Tetsu Akimoto, Ryoko Horikoshi, Shigeaki Muto, Eiji Kusano 
 Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan

Correspondence Address:
Tetsu Akimoto
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-Shi, Tochigi 329-0498
Japan

We describe a 19-year-old male who developed diclofenac-induced acute inters­titial nephritis (AIN). Diffuse mononuclear cell infiltration was confirmed by renal biopsy and a Gallium (Ga)-67 scintigraphy revealed diffuse uptake of the isotope in both kidneys. His renal function had gradually and promptly recovered after initiation of low-dose prednisolone (0.5 mg/kg/day). There are no established criteria for the administration of corticosteroids in the treatment of drug-induced AIN. Moreover, no clear recommendations regarding the optimal dose and duration of steroid administration in the treatment for drug-induced AIN has been established. In addition, we discuss the clinical benefit of steroid treatment and the diagnostic impact of Ga scanning on the management of drug-induced AIN.


How to cite this article:
Akimoto T, Horikoshi R, Muto S, Kusano E. Low-dose corticosteroid and gallium-67 scintigraphy and acute interstitial nephritis.Saudi J Kidney Dis Transpl 2014;25:864-868


How to cite this URL:
Akimoto T, Horikoshi R, Muto S, Kusano E. Low-dose corticosteroid and gallium-67 scintigraphy and acute interstitial nephritis. Saudi J Kidney Dis Transpl [serial online] 2014 [cited 2022 Jan 19 ];25:864-868
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2014;volume=25;issue=4;spage=864;epage=868;aulast=Akimoto;type=0