Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2016  |  Volume : 27  |  Issue : 2  |  Page : 407--410

Quadriparesis due to Gitelman俟Q製 syndrome diagnosed with thiazide diuretic test response


Sumanto Mukhopadhyay, Suvendu Jana, Apratim Chatterjee, Manoj Roy, Anup Sarkar, Jotideb Mukhopadhyay 
 Department of Internal Medicine, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India

Correspondence Address:
Sumanto Mukhopadhyay
Department of Internal Medicine, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal
India

Gitelman俟Q製 syndrome is characterized by hypocalciuria, severe hypomagnesemia, and prominent muscular involvements such as fatigue, weakness, cramps, and tetany. It is due to mutations in the thiazide sensitive NaCl co-transporter in the distal convoluted tubule. The administration of thiazide diuretics may induce a subnormal increase of urinary Cl excretion in patients with Gitelman俟Q製 syndrome, consistent with the hypothesis that less than normal Cl is reabsorbed by the thiazide-inhibitable transporter in Gitelman俟Q製 syndrome. Thus, we report a case of Gitelman俟Q製 syndrome presenting with quadriparesis diagnosed by using thiazide clearance test.


How to cite this article:
Mukhopadhyay S, Jana S, Chatterjee A, Roy M, Sarkar A, Mukhopadhyay J. Quadriparesis due to Gitelman's syndrome diagnosed with thiazide diuretic test response.Saudi J Kidney Dis Transpl 2016;27:407-410


How to cite this URL:
Mukhopadhyay S, Jana S, Chatterjee A, Roy M, Sarkar A, Mukhopadhyay J. Quadriparesis due to Gitelman's syndrome diagnosed with thiazide diuretic test response. Saudi J Kidney Dis Transpl [serial online] 2016 [cited 2020 Nov 29 ];27:407-410
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=2;spage=407;epage=410;aulast=Mukhopadhyay;type=0