Saudi Journal of Kidney Diseases and Transplantation

BRIEF COMMUNICATION
Year
: 2017  |  Volume : 28  |  Issue : 1  |  Page : 95--101

Visceral leishmaniasis in adults with nephropathy


H Kaaroud El Jeri1, A Harzallah1, S Barbouch1, MM Bacha1, R Kheder2, S Turki1, S Trabelsi3, E Abderrahim1, F Ben Hamida4, T Ben Abdallah1 
1 Department of Medicine A, Charles Nicolle Hospital; Faculty of Medicine, Tunis El Manar University, Tunis, Tunisia
2 Department of Nephrology, La Rabta Hospital; Faculty of Medicine, Tunis El Manar University, Tunis, Tunisia
3 Department of Parasitology, Charles Nicolle Hospital; Faculty of Medicine, Tunis El Manar University, Tunis, Tunisia
4 Laboratory of Renal Pathology LR00SP01, Charles Nicolle Hospital; Faculty of Medicine, Tunis El Manar University, Tunis, Tunisia

Correspondence Address:
A Harzallah
Department of Medicine A, Charles Nicolle Hospital, Tunis
Tunisia

The aim of this study is to evaluate the features of visceral leishmaniasis (VL) in adults with nephropathy, who were not infected with the human immunodeficiency virus. This is a retrospective study of 14 adults hospitalized between 2000 and 2014, with VL and renal involvement. Clinical, biological, and therapeutic data were collected from the patients«SQ» medical files. Eleven women and three men, most of whom were from the North of the country, with a mean age of 40.5 years were studied. Lupus was present in five cases, the Sicca syndrome in three cases, diabetes in one case, renal failure on dialysis in two cases, and there were three renal transplant recipients. Major clinical symptoms were fever and weakness in all cases. Enlargement of the spleen was present in eight cases and hepatomegaly in six cases. Biologic inflammatory syndrome and anemia were present in all cases, and pancytopenia was present in seven cases. Renal insufficiency was noted in all cases. Diagnosis of VL was confirmed by bone marrow examination or serology. Treatment consisted of antimoniate in 10 cases and amphotericin B in four cases. Seven deaths were recorded. Clinical symptoms of VL are atypical in patients with nephropathy and therefore, the diagnosis should be suspected in such patients because VL is still endemic in our country.


How to cite this article:
El Jeri H K, Harzallah A, Barbouch S, Bacha M M, Kheder R, Turki S, Trabelsi S, Abderrahim E, Hamida F B, Abdallah T B. Visceral leishmaniasis in adults with nephropathy.Saudi J Kidney Dis Transpl 2017;28:95-101


How to cite this URL:
El Jeri H K, Harzallah A, Barbouch S, Bacha M M, Kheder R, Turki S, Trabelsi S, Abderrahim E, Hamida F B, Abdallah T B. Visceral leishmaniasis in adults with nephropathy. Saudi J Kidney Dis Transpl [serial online] 2017 [cited 2020 Nov 30 ];28:95-101
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2017;volume=28;issue=1;spage=95;epage=101;aulast=El;type=0