Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2017  |  Volume : 28  |  Issue : 2  |  Page : 415--424

Vasculitis and vasculopathy in Lupus Nephritis: Clinical variability, outcome, and new insight into treatment


A Kaul1, V Agrawal2, D Bhaduaria1, Vikas Agrawal3, Narayan Prasad1, Amit Gupta1, RK Sharma1 
1 Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
2 Department of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
3 Department of Immunology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India

Correspondence Address:
A Kaul
Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh
India

More than 50% of patients with systemic lupus erythematosus (SLE) have renal involvement at presentation or during their illness. Lupus nephritis (LN) encompasses several patterns of renal disease, including glomerular, tubulointerstitial, and vascular pathologies. The presence and significance of renal vascular lesions (VLs) are often overlooked. VLs in LN are not rare with an incidence of 10%–40% on renal biopsies from various studies and their presence is often labeled as poor prognostic markers. The current treatment protocol for LN is mainly based on the glomerular pathology, and no guidelines/consensus exists for treatment of LN with VLs. We describe the clinical presentation, course, response to therapy, and outcomes in five patients with SLE with histological evidence of renal VLs.


How to cite this article:
Kaul A, Agrawal V, Bhaduaria D, Agrawal V, Prasad N, Gupta A, Sharma R K. Vasculitis and vasculopathy in Lupus Nephritis: Clinical variability, outcome, and new insight into treatment.Saudi J Kidney Dis Transpl 2017;28:415-424


How to cite this URL:
Kaul A, Agrawal V, Bhaduaria D, Agrawal V, Prasad N, Gupta A, Sharma R K. Vasculitis and vasculopathy in Lupus Nephritis: Clinical variability, outcome, and new insight into treatment. Saudi J Kidney Dis Transpl [serial online] 2017 [cited 2021 Jun 21 ];28:415-424
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2017;volume=28;issue=2;spage=415;epage=424;aulast=Kaul;type=0