Saudi Journal of Kidney Diseases and Transplantation

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 31  |  Issue : 5  |  Page : 927--936

Prevalence, Location, and Determinants of Valvular Calcifications in Congolese Patients on Chronic Hemodialysis: A Multicenter Cross-Sectional Study


Yannick M Engole1, Yves N Lubenga2, Yannick M Nlandu1, Jean Robert R. Makulo1, Vieux M Mokoli1, Charles K Kahindo1, Marie France I. Mboliasa1, Evariste M Kadima1, Augustin L Longo1, Aliocha. Nkodila1, Justine B Bukabau1, François B Lepira1, Nazaire M Nseka1, Ernest K Sumaili1 
1 Nephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of Congo
2 Cardiology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of Congo

Correspondence Address:
Yannick M Engole
Nephrology Unit, University Hospital of Kinshasa, Kinshasa
Democratic Republic of Congo

Valvular calcifications (VCs) are one of the major cardiovascular complications in patients on chronic hemodialysis (HD) due to its prevalence and predictive morbidity and mortality. The current study assessed the prevalence, location, and risk factors of VC among chronic HD Congolese patients in Kinshasa. This observational study involved three HD centers in Kinshasa between March and August 2016. Consecutive consenting adults on maintenance HD for at least six months were recruited. VCs were defined as a luminous echo on one or more cusps of the aortic or mitral valve. Risk factors of VC were determined by multivariate analysis. Sixty patients (mean age: 52.5 ± 15.9 years) were enrolled. The mean serum calcium and phosphorus were7.9 ± 1.3 mg/dL and 5.7 ± 1.7 mg/dL, respectively. VCs were encountered in 38% of the whole group in aortic and mitral valvular location in 64% and 23%, respectively. Hypertension, age >60 years, tobacco use, and hyperphosphatemia were independently associated with VC. Despite a young age of patients, VCs were a common finding and associated with both traditional and chronic kidney disease-specific risk factors.


How to cite this article:
Engole YM, Lubenga YN, Nlandu YM, R. Makulo JR, Mokoli VM, Kahindo CK, I. Mboliasa MF, Kadima EM, Longo AL, Nkodila A, Bukabau JB, Lepira FB, Nseka NM, Sumaili EK. Prevalence, Location, and Determinants of Valvular Calcifications in Congolese Patients on Chronic Hemodialysis: A Multicenter Cross-Sectional Study.Saudi J Kidney Dis Transpl 2020;31:927-936


How to cite this URL:
Engole YM, Lubenga YN, Nlandu YM, R. Makulo JR, Mokoli VM, Kahindo CK, I. Mboliasa MF, Kadima EM, Longo AL, Nkodila A, Bukabau JB, Lepira FB, Nseka NM, Sumaili EK. Prevalence, Location, and Determinants of Valvular Calcifications in Congolese Patients on Chronic Hemodialysis: A Multicenter Cross-Sectional Study. Saudi J Kidney Dis Transpl [serial online] 2020 [cited 2021 Sep 21 ];31:927-936
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2020;volume=31;issue=5;spage=927;epage=936;aulast=Engole;type=0