Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2020  |  Volume : 31  |  Issue : 6  |  Page : 1415--1419

The significance of anti-phospholipase receptor antibodies in a patient with membranous nephropathy


Jayaprakash R Dasari1, Pallavi Reddy2, Yeshwanter Radhakrishnan2, Nikhil Nair3, Ronith Chakraborty4, Lena Nemer5, Rupesh Raina6 
1 Department of Nephrology, Americare Kidney Institute, Akron, USA
2 Department of Internal Medicine, Akron General Medical Center, Akron, USA
3 Department of Chemistry, Case Western Reserve University, Cleveland, Ohio, USA
4 Department of Chemistry, Eastern Michigan University Ypsilanti, Michigan, USA
5 Department of Internal Medicine, University of Missouri-Kansas City School of Medicine, Kansas City, USA
6 Department of Nephrology, Akron Nephrology Associates/Cleveland Clinic Akron General; Department of Nephrology, Akron Children’s Hospital, Akron, Ohio, USA

Correspondence Address:
Nikhil Nair
Department of Chemistry, Case Western Reserve University, Cleveland, Ohio
USA

Membranous nephropathy (MN) is the major cause of nephrotic syndrome in adults and may be secondary to systemic lupus erythematosus or malignancy in 25% of patients. Without any etiology, it is called primary MN, which is usually associated with phospholipase A2 (PLA2) receptor antibodies. Secondary MN can appear months before a secondary cause is identified. Here, we report a case of MN, that was found to be secondary to pancreatic adenocarcinoma and positive for PLA2 receptor antibodies.


How to cite this article:
Dasari JR, Reddy P, Radhakrishnan Y, Nair N, Chakraborty R, Nemer L, Raina R. The significance of anti-phospholipase receptor antibodies in a patient with membranous nephropathy.Saudi J Kidney Dis Transpl 2020;31:1415-1419


How to cite this URL:
Dasari JR, Reddy P, Radhakrishnan Y, Nair N, Chakraborty R, Nemer L, Raina R. The significance of anti-phospholipase receptor antibodies in a patient with membranous nephropathy. Saudi J Kidney Dis Transpl [serial online] 2020 [cited 2021 Apr 20 ];31:1415-1419
Available from: https://www.sjkdt.org/article.asp?issn=1319-2442;year=2020;volume=31;issue=6;spage=1415;epage=1419;aulast=Dasari;type=0